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The Association between Age-Related Changes in Oral Neuromechanics and Alzheimer's Disease
1Department of Organismal Biology and Anatomy, University of Chicago, 1027 East 57th Street (Anatomy Suite 303),Chicago, IL 60637, USA.
Abstract:
The global population of 80 years and older is predicted to reach 437 million by 2050. As overall brain structure and function progressively degrades, older and younger adults show differences in sensorimotor performance and brain activity in the sensorimotor regions. Oral sensorimotor functions are an important area of focus in natural aging and Alzheimer's Disease (AD) because oral health issues are commonly found in both elderly and AD populations. While human behavioral studies on changes in oral sensorimotor functions abound, very little is known about their neuronal correlates in normal and pathological aging.
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