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COVID-19 vaccination in haematology patients: an Australian and New Zealand consensus position statement

Georgia McCaughan1,2, Pietro Di Ciaccio1,2, Michelle Ananda-Rajah3,4

  • 1Department of Haematology, St Vincent's Hospital, Sydney, New South Wales, Australia.

Internal Medicine Journal
|May 28, 2021
PubMed

Insights

Patients with blood disorders should receive early COVID-19 vaccines due to high infection risks. However, vaccination should not replace other public health measures as effectiveness in these groups is unknown.

Area of Science:

  • Hematology
  • Infectious Diseases
  • Vaccinology

Background:

  • Australia and New Zealand have controlled COVID-19 community transmission.
  • COVID-19 vaccination rollout is imminent in both countries.
  • Patients with hematological disorders are at increased risk of severe COVID-19 outcomes.

Purpose of the Study:

  • Provide a consensus position statement on COVID-19 vaccination for patients with hematological disorders.
  • Recommend expedited access to high-efficacy COVID-19 vaccines for at-risk hematology patients.
  • Highlight the need for ongoing data collection on vaccine safety and efficacy in this population.

Main Methods:

  • Collaboration between the Haematology Society of Australia and New Zealand and infectious diseases specialists.
  • Development of a consensus position statement based on current knowledge and risk assessment.
  • Review of existing data regarding COVID-19 risk in hematological disorders.

Main Results:

  • Recommended expedited access to high-efficacy COVID-19 vaccines for patients with hematological malignancies and certain benign hematological disorders.
  • Stressed that vaccination should not replace existing public health measures for these patients.
  • Acknowledged the unknown effectiveness of COVID-19 vaccines in patients with hematological malignancies.

Conclusions:

  • Patients with hematological disorders are a priority group for COVID-19 vaccination.
  • Further research is crucial to determine the specific safety and efficacy profiles of COVID-19 vaccines in hematology patients.
  • Continued vigilance with public health measures is essential alongside vaccination efforts.

Keywords:
COVID-19haematologyleukaemialymphomaplasma cellvaccination

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