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[A new alkaloid from Ervatamia hainanensis]
Zi-Wei Li1, Chen-Chen Sang1, Biao Sun1
1Institute of Traditional Chinese Medicine & Natural Products, and Guangdong Engineering Research Center for Modernization of Traditional Chinese Medicine(TCM), College of Pharmacy, Jinan University Guangzhou 510632, China.
Abstract:
In order to study the alkaloids from branches and leaves of Ervatamia hainanensis, silica gel, ODS, Sephadex LH-20 and HPLC chromatography were used to obtain six alkaloids from the branches and leaves of E. hainanensis with use of. Based on the physicochemical properties and spectral data, their structures were identified as 10-hydroxydemethylhirsuteine(1), 3R-hydroxycoronaridine(2), 3-(2-oxopropyl)coronaridine(3), pandine(4), 16-epi-vobasine(5), and 16-epi-vobasinic acid(6). Among them, compound 1 was a new monoterpenoid indole alkaloid, and compounds 5 and 6 were obtained from this plant for the first time.
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