Related Experiment Video
Updated: Nov 4, 2025

Echocardiographic Characterization of Left Ventricular Structure, Function, and Coronary Flow in Neonate Mice
Published on: April 7, 2022
A novel echocardiographic approach for assessing coronary artery origins
Christopher DeZorzi1,2, Alan Marsh1, Tracy Binkley1
1Department of Cardiology, Saint Luke's Mid America Heart Institute, Kansas City, MO, USA.
Insights
Biplane echocardiography improves confidence in identifying coronary artery origins, aiding in pre-participation athletic screening for anomalous aortic origin of a coronary artery (AAOCA) and reducing sudden cardiac death risk.
Area of Science:
- Cardiology
- Medical Imaging
- Sports Medicine
Background:
- Anomalous aortic origin of a coronary artery (AAOCA) is a critical cause of sudden cardiac death (SCD) in athletes.
- Identifying coronary artery origins is vital for pre-participation athletic screening.
- Current echocardiography protocols for AAOCA detection are time-consuming and lack reader confidence.
Purpose of the Study:
- To evaluate the impact of biplane echocardiographic imaging on reader confidence in identifying coronary artery origins.
- To assess the effectiveness of biplane imaging in improving diagnostic accuracy for AAOCA.
Main Methods:
- A review of echocardiographic images from 110 competitive athletes (ages 13-22).
- Six echocardiographers with varying experience assessed coronary artery origins using single-plane and then biplane imaging.
- Readers rated their confidence (1-5) in identifying coronary artery origins.
Main Results:
- Mean reader confidence increased by 0.4 points (P=0.05) with biplane versus single-plane imaging.
- Between-reader variability in confidence decreased significantly from 25.9% to 10.3%.
Conclusions:
- Biplane echocardiographic imaging enhances reader confidence in identifying coronary artery origins.
- This improved confidence can lead to more reliable screening for AAOCA in athletes.
- Biplane imaging offers a more consistent and confident approach to diagnosing AAOCA.
Introduction:
Anomalous aortic origin of a coronary artery (AAOCA) is a potential etiology of sudden cardiac death (SCD) in physically active individuals. Identification of coronary artery origins is an essential part of comprehensive pre-participation athletic screening. Although echocardiography is an established method for identifying AAOCA, current imaging protocols are time intensive and readers frequently have low confidence in coronary artery identification.
Methods:
Echocardiographic images from a sample of 110 patients from a database of competitive athletes ages 13-22 years from the Kansas City metropolitan area were reviewed by six echocardiographers of varying experience. Coronary artery images were provided to the readers in the conventional single plane for all the patients; then biplane images of the same patients were presented to the readers. While reviewing the images, readers recorded perceived confidence level of identifying the coronary artery from 1 (least confident) to 5 (most confident). Ratings and differences between ratings were summarized descriptively by means and standard deviations across all readings as well as by individual reader.
Results:
The mean confidence level of echocardiogram readers in identifying coronary artery origins increased by 0.4 points (P = .05) on a five-point confidence scale when using biplane imaging rather than single plane imaging. When assessing the variability of confidence of readers on the same patient, the between-reader variability improved from 25.9% to 10.3%.
Conclusions:
Biplane echocardiographic imaging increases the confidence of readers in identifying coronary artery origins.
Related Concept Videos
Acute Coronary Syndrome III: Diagnostic Studies
Imaging Studies for Cardiovascular System I:Echocardiography
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
Imaging Studies for Cardiovascular System II:Types of Echocardiography
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for...
Coronary Circulation
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
Assessment of apical radial pulse
The A-R pulse assessment involves simultaneous evaluation of the apical and radial pulses. When the apical and radial pulse rates vary, this assessment helps identify a pulse deficit.
Pre-Procedural Preparation

