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Published on: May 5, 2023
Pathology of intraductal papillary mucinous neoplasms
Naziheh Assarzadegan1, Elizabeth Thompson1, Kevan Salimian1
1Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD, 21212, USA.
Background:
Intraductal papillary mucinous neoplasms (IPMNs) represent a unique opportunity to treat and prevent a curable neoplasm before it has the chance to progress to incurable cancer. This prospect, however, has to be balanced with the real risk of over treating patients with lesions that would, in fact, never progress during the life of the patient.
Purpose:
Informed clinical decisions in the treatment of IPMNs are first and foremost based on a deep understanding of the pathology of these lesions.
Conclusions:
Here we review the pathology of IPMNs, with an emphasis on the clinical relevance of the important features that characterize these lesions.
