Related Experiment Video
Updated: Nov 4, 2025

Evaluation of a Reliable Biomarker in a Cecal Ligation and Puncture-Induced Mouse Model of Sepsis
Published on: December 9, 2022
Sepsis Biomarkers
Yachana Kataria1, Daniel Remick2
1Department of Pathology and Laboratory Medicine, Boston School of Medicine, Boston, MA, USA. Yachana.Kataria@bmc.org.
Abstract:
Biomarkers have been used in sepsis to assist with the diagnosis of disease as well as determining the severity of disease, that is, prognosis. These biomarkers are based on the presence of discrete molecules within the blood. Unfortunately, in 2020, a single biomarker does not have sufficient sensitivity and specificity to definitively rule in or rule out sepsis. Biomarkers have shown better performance in animal models of disease.
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