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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
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New Daily Persistent Headache in a Pediatric Population

Eric Strong1, Emily Linda Pierce1, Raquel Langdon1

  • 18404Children's National Hospital, Washington, DC, USA.

Journal of Child Neurology
|May 28, 2021
PubMed

Insights

New daily persistent headache (NDPH) is common in children, often presenting with migraine features and difficulty in treatment. Many pediatric NDPH patients experience medication overuse headaches and fail multiple therapies.

Area of Science:

  • Neurology
  • Pediatric Headache Medicine
  • Clinical Research

Background:

  • New daily persistent headache (NDPH) is a primary headache disorder defined by daily, unremitting headaches for over 3 months.
  • Limited research exists on NDPH characteristics specifically within the pediatric population.

Purpose of the Study:

  • To characterize NDPH in pediatric patients presenting to a tertiary care headache program.
  • To identify demographic, clinical features, and treatment outcomes for pediatric NDPH.

Main Methods:

  • Retrospective analysis of pediatric patients diagnosed with NDPH between 2016-2018.
  • Data collected from an institutional review board-approved patient registry at a tertiary referral center.

Main Results:

  • NDPH affected 14% of the pediatric headache population (245 patients), predominantly females (78%) and white (72%).
  • Median age was 14.8 years, with a median pain intensity of 6/10.
  • Migrainous features (photophobia, phonophobia, reduced activity) were common (85-88%).
  • High rates of treatment failure were observed: 33% failed preventive and 56% failed abortive medications.
  • 36% of patients developed medication overuse headache.

Conclusions:

  • NDPH is a significant condition in pediatric chronic headache sufferers.
  • Pediatric NDPH frequently exhibits migrainous features and is resistant to treatment.
  • High rates of medication overuse headache and failed management highlight treatment challenges.
Abstract

Keywords:
chronic headacheintractable headachenew daily persistent headachepediatric headache

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