Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Overview of Lipid Metabolism01:24

Overview of Lipid Metabolism

3.5K
Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
3.5K
Lipid Digestion01:06

Lipid Digestion

96.1K
Lipids are large molecules that are generally not water-soluble. Since most of the digestive enzymes in the human body are water-based, there are specific steps the body must take to break down lipids and make them available for use.
96.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preclinical safety assessment and immunological evaluation of xenogeneic mammary cells of porcine origin, utilized as an intralesional immunotherapeutic agent.

Cell transplantation·2026
Same author

Very Low-density Lipoprotein-triacylglyceride Promotes Hepatitis B Virus Reactivation.

Journal of physiological investigation·2026
Same author

Prevention of Porcine Epidemic Diarrhea Virus With Nanotube-Adjuvanted Oral DNA Vaccines.

Transboundary and emerging diseases·2026
Same author

ImmiR: A database of microRNAs associated with immune checkpoints and infiltrates.

Computational and structural biotechnology journal·2025
Same author

Validation of the electrical potential method for the liquid metal local velocity and temperature measurements under the magnetic field.

The Review of scientific instruments·2025
Same author

Saline and N-acetylcysteine-based strategies and other approaches to prevent the risk of CA-AKI: a meta-analysis.

Frontiers in medicine·2025
Same journal

VeloRM: disentangling pre- and post-splicing RNA modification dynamics at single-cell resolution.

Nucleic acids research·2026
Same journal

Accessibility of telomeric overhangs to stabilizing small-molecule ligands.

Nucleic acids research·2026
Same journal

Multivalent interactions mediate SNAIL transcription factor stimulation of the nucleosome deacetylase activity of the CoREST complex.

Nucleic acids research·2026
Same journal

Genome-wide mapping of DNA G-quadruplexes in Trypanosoma brucei chromatin reveals enrichment in coding regions and transcription start sites.

Nucleic acids research·2026
Same journal

Epigenetic landscape of synthetic human centromere core regions: CENP-A assembly and euchromatic modifications interdependently antagonize heterochromatin accumulation.

Nucleic acids research·2026
Same journal

MAPK/ERK signaling regulates H3K9me3 heterochromatin reorganization to confer mesendoderm developmental competence.

Nucleic acids research·2026
See all related articles

Related Experiment Video

Updated: Nov 4, 2025

Quantitative Analysis of the Cellular Lipidome of Saccharomyces Cerevisiae Using Liquid Chromatography Coupled with Tandem Mass Spectrometry
08:56

Quantitative Analysis of the Cellular Lipidome of Saccharomyces Cerevisiae Using Liquid Chromatography Coupled with Tandem Mass Spectrometry

Published on: March 8, 2020

7.6K

LipidSig: a web-based tool for lipidomic data analysis.

Wen-Jen Lin1, Pei-Chun Shen2, Hsiu-Cheng Liu2

  • 1Graduate Institute of Biomedical Science, China Medical University, Taichung 40403, Taiwan.

Nucleic Acids Research
|May 28, 2021
PubMed
Summary
This summary is machine-generated.

LipidSig is a new web server that simplifies lipidomic data analysis by classifying lipids and exploring their biological functions. This tool helps researchers identify significant lipid features for advancing lipid biology research.

More Related Videos

Shotgun Lipidomics of Rodent Tissues
11:46

Shotgun Lipidomics of Rodent Tissues

Published on: November 18, 2022

2.3K
Navigating the Mass Spectrometry-Based Proteomic Data Using Free Computational Tools
07:01

Navigating the Mass Spectrometry-Based Proteomic Data Using Free Computational Tools

Published on: August 19, 2025

341

Related Experiment Videos

Last Updated: Nov 4, 2025

Quantitative Analysis of the Cellular Lipidome of Saccharomyces Cerevisiae Using Liquid Chromatography Coupled with Tandem Mass Spectrometry
08:56

Quantitative Analysis of the Cellular Lipidome of Saccharomyces Cerevisiae Using Liquid Chromatography Coupled with Tandem Mass Spectrometry

Published on: March 8, 2020

7.6K
Shotgun Lipidomics of Rodent Tissues
11:46

Shotgun Lipidomics of Rodent Tissues

Published on: November 18, 2022

2.3K
Navigating the Mass Spectrometry-Based Proteomic Data Using Free Computational Tools
07:01

Navigating the Mass Spectrometry-Based Proteomic Data Using Free Computational Tools

Published on: August 19, 2025

341

Area of Science:

  • Biochemistry
  • Bioinformatics
  • Systems Biology

Background:

  • Lipidomic studies are rapidly expanding, necessitating advanced tools for data analysis.
  • Lipids possess unique characteristics (e.g., class, double bonds, chain length) that dictate their biological functions.
  • Current analysis workflows can be complex, hindering comprehensive lipid characteristic exploration.

Purpose of the Study:

  • To develop a user-friendly web server, LipidSig, for streamlined lipidomic data analysis.
  • To enhance the exploration of lipid characteristics and their biological relevance.
  • To facilitate the identification of significant lipid-related features in cellular and disease phenotypes.

Main Methods:

  • Developed LipidSig, a web server with five integrated modules: Profiling, Differential Expression, Correlation, Network, and Machine Learning.
  • Implemented a novel function for converting between lipid species and user-defined characteristics.
  • Integrated analyses for fatty acid properties and multiple lipid characteristics.

Main Results:

  • LipidSig provides a flexible and user-friendly platform for comprehensive lipidomic data analysis.
  • The conversion function enables efficient data mining for individual lipids and characteristic subgroups.
  • The server supports the evaluation of lipid effects on cellular or disease phenotypes.

Conclusions:

  • LipidSig is a valuable tool for simplifying lipidomic analysis and advancing lipid biology.
  • The web server facilitates the identification of significant lipid biomarkers and functional insights.
  • LipidSig is freely accessible, promoting wider adoption and research advancement.