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Related Experiment Videos

[Pseudophakic bullous keratopathy].

F Bigar1, J Stürmer, R Ganzfried

  • 1Universitäts-Augenklinik Zürich.

Klinische Monatsblatter Fur Augenheilkunde
|May 1, 1988
PubMed
Summary
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Cataract surgery with intraocular lens implantation is increasing. Pseudophakic bullous keratopathy, a rare complication, is more common with anterior chamber lenses than posterior chamber lenses.

Area of Science:

  • Ophthalmology
  • Corneal Surgery
  • Intraocular Lens Technology

Context:

  • Cataract extraction rates in Switzerland have tripled since 1981.
  • Intraocular lens (IOL) implantation accompanies 95% of cataract surgeries.
  • Pseudophakic bullous keratopathy (PBK) is a rare but serious complication.

Purpose:

  • To analyze the incidence and trends of pseudophakic bullous keratopathy (PBK) as an indication for keratoplasty.
  • To compare the time to keratoplasty for corneal decompensation based on IOL type.
  • To assess long-term endothelial cell density in patients with specific IOLs.

Summary:

  • Between 1980-1986, only 20 keratoplasties were performed for PBK at the authors' clinic.
  • Penetrating keratoplasty for corneal decompensation occurs sooner after posterior chamber IOLs (1 year) than anterior chamber IOLs (3 years) or iris-supported IOLs (4 years).

Related Experiment Videos

  • The incidence of PBK with posterior chamber IOLs in Switzerland is 0.1-0.3%.
  • A 7-year study of 16 patients with Binkhorst two-loop lenses showed stable endothelial cell density (~1600 cells/mm²).

    • Impact:

    • Highlights the rarity of PBK despite increased cataract surgery rates.
    • Provides evidence for the association between IOL type and the timing of subsequent corneal transplantation.
    • Suggests favorable long-term endothelial cell survival with certain IOL designs, informing clinical practice and patient selection.