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Published on: July 26, 2024
Considerations for carotid artery disease management in a frail population
1VA Boston Healthcare System, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Insights
Carotid artery stenosis management in older adults can be complex. Frailty assessment aids shared decision-making for revascularization, optimizing treatment for this population.
Area of Science:
- Vascular Surgery
- Geriatrics
- Interventional Cardiology
Background:
- Carotid artery stenosis is common in older adults, with treatment options including medical therapy and revascularization (CEA, CAS, TCAR).
- The benefit of revascularization in asymptomatic patients with carotid artery stenosis remains uncertain.
- Minimally invasive techniques expand revascularization candidacy, but procedural risks persist, especially in older adults with comorbidities.
Purpose of the Study:
- To review the management of carotid artery stenosis in older adults.
- To explore the relationship between frailty and carotid artery stenosis treatment decisions.
- To discuss integrating frailty assessment into shared decision-making for optimal patient care.
Main Methods:
- Literature review on carotid artery stenosis management in older adults.
- Analysis of the role of frailty assessment in clinical decision-making.
- Discussion of shared decision-making models incorporating frailty.
Main Results:
- Frailty assessment can identify older adults who may not benefit from or tolerate revascularization procedures.
- Integrating frailty into shared decision-making enhances personalized treatment planning for carotid artery stenosis.
- Novel revascularization techniques offer options but require careful risk-benefit analysis, particularly in frail individuals.
Conclusions:
- Frailty assessment is a valuable tool for guiding treatment decisions in older adults with carotid artery stenosis.
- Shared decision-making, informed by frailty, is crucial for optimizing outcomes in this patient group.
- Personalized management strategies are essential, considering both stenosis severity and patient-specific factors like frailty.
Abstract:
Carotid artery stenosis is highly prevalent in older adults. Generally, symptomatic patients are treated with medical therapy and revascularization by either a carotid endarterectomy (CEA), carotid artery stent (CAS), or transcarotid artery revascularization (TCAR). In asymptomatic patients it remains unclear whether revascularization is beneficial. Novel and less invasive techniques mitigate some of the risk of revascularization, allowing patients who previously were too high risk to now be candidates. Despite this, any invasive procedure has risks and potential for complications. Furthermore, it can be unclear whether certain patient populations, such as older adults and those with multiple chronic medical conditions will derive benefit from an intervention. Frailty is an assessment tool that can be used to guide decision-making process for older patients. In this review we discuss the management of carotid artery stenosis in older adults, its relationship with frailty, and how a frailty assessment can be integrated into the shared decision-making process to determine the optimal treatment plan for each patient.
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