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Medicine consumptions and occupational road risk
Manon Bourdeau1, Nicolas Guibert2, Emmanuel Fort1
1University of Lyon, University of Lyon 1, University of Gustave Eiffel, UMRESTTE, UMR T_9405, F- 69373, Lyon, France.
Accident; Analysis and Prevention
|May 29, 2021
Summary
Driving after taking certain medications increases crash risk, especially during occupational journeys. Preventive measures are needed for drivers on commuting or mission trips using antiepileptics, psycholeptics, psychoanaleptics, and other nervous system drugs.
Area of Science:
- Road safety research
- Pharmacovigilance
- Occupational health
Background:
- Medication use is linked to increased road traffic crash risk.
- Data on crash risk by journey type (private, commuting, mission) and medication is limited.
- Occupational drivers may exhibit different medication use and coping behaviors.
Purpose of the Study:
- To investigate the association between exposure to ten classes of medicines and the risk of being responsible for a road traffic crash.
- To differentiate this risk based on journey type: private, commuting, or mission.
Main Methods:
- Utilized French national databases: crash, police reports, and health insurance.
- Analyzed data from 179,269 drivers (18-65 years) involved in injurious crashes (2005-2015).
- Employed logistic regression models stratified by journey type, adjusting for confounders.
Main Results:
- Higher crash responsibility risk observed for antiepileptics, psycholeptics, psychoanaleptics, and other nervous system drugs during occupational journeys (commuting/mission) compared to private journeys.
- Odds Ratios (OR) for antiepileptics were 1.59 (mission), 1.63 (commuting), and 1.47 (private).
- Other nervous system drugs showed an OR of 2.04 for mission journeys versus 1.43 for private journeys.
Conclusions:
- Findings highlight a differential risk associated with medication use depending on the type of journey.
- Results support the implementation of targeted preventive measures for specific medications during occupational travel.
- Further research and interventions are warranted to mitigate medication-related crash risks for occupational drivers.
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