Related Experiment Video
Updated: Nov 4, 2025

Author Spotlight: PEGASOS Tissue Clearing Technique to Visualize Bone Remodeling
Published on: August 18, 2023
Craniosynostosis: Posterior Cranial Vault Remodeling
Laura S Humphries1, Jordan W Swanson2, Scott P Bartlett2
1Division of Plastic and Reconstructive Surgery, University of Mississippi Medical Center, Children's of Mississippi Hospital, 2500 N. State Street, Jackson, MS 39216, USA. Electronic address: https://twitter.com/ls_humphries.
Posterior cranial vault distraction osteogenesis offers a reliable method for intracranial expansion, especially for syndromic craniosynostosis. This technique allows gradual bone expansion, achieving greater volumetric increases with fewer complications than traditional methods.
Area of Science:
- Neurosurgery
- Craniofacial Surgery
- Pediatric Surgery
Background:
- Syndromic craniosynostosis often presents with complex skull deformities requiring surgical intervention.
- Turribrachycephaly, a specific deformity, necessitates methods for significant intracranial volume expansion.
- Conventional techniques may have limitations in achieving desired volumetric gains and remodeling.
Purpose of the Study:
- To evaluate posterior cranial vault distraction osteogenesis as a method for intracranial expansion.
- To assess its efficacy in treating turribrachycephaly associated with syndromic craniosynostosis.
- To compare its outcomes with conventional surgical techniques.
Main Methods:
- Posterior cranial vault distraction osteogenesis involves gradual expansion of the posterior skull.
- The technique allows for controlled bone lengthening over several weeks.
- Soft tissues are stretched to accommodate increased intracranial volume.
Main Results:
- Achieves significant volumetric expansion of the intracranial space.
- Demonstrates a powerful, reliable, and low-morbidity approach.
- Offers a more gradual remodeling modality with infrequent complications.
- Preserves the frontal cranium for potential future frontofacial procedures.
Conclusions:
- Posterior cranial vault distraction osteogenesis is an effective treatment for turribrachycephaly in syndromic craniosynostosis.
- It provides greater volumetric expansion compared to conventional methods.
- The procedure is associated with a low complication rate, though device removal requires a second surgery.
Related Concept Videos
Cranial Bones: Superior and Posterior View
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
Sutures of the Skull
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Cranial Bones: Lateral View
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
Overview of the Skull
The cranial vault surrounds and protects the brain and houses the middle and inner ear structures. This cavity is bounded superiorly by the rounded top of the skull, which...
Bone Formation by Intramembranous Ossification
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
Cranial and Spinal Meninges
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...

