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Contact X-ray brachytherapy for rectal cancer: Past, present, and future
J-P Gérard1, N Barbet2, C Dejean1
1Centre Antoine-Lacassagne, 33, avenue de Valombrose, 06000 Nice, France.
Abstract:
The Papillon experience and the Lyon R96-02 trial have shown that contact X-ray brachytherapy of 50kV is efficient and safe to achieve long term local control and organ preservation for cT1 and early cT2-3 rectal cancers. The OPERA trial, using the Papillon 50™ machine, brings further support to this preservation strategy for selected T2T3ab lesions. Future trials using a contact X-ray boost will try to consolidate and enlarge its place in organ preservation for rectal cancers.
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