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Structure-activity relationship and biological evaluation of berberine derivatives as PCSK9 down-regulating agents

Tian-Yun Fan1, Yu-Xin Yang1, Qing-Xuan Zeng1

  • 1Institute of Medicinal Biotechnology, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 10050, China.

Bioorganic Chemistry
|May 30, 2021
PubMed

Keywords:
BerberineLDL-CPCSK9Structure–activity relationshipTranscriptional inhibition

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