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Risk Factors for Increased Post-operative Length of Stay in Children with Coarctation of Aorta
Laura Schoeneberg1, Parthak Prodhan1, Beverly Spray2
1Department of Pediatrics (Cardiology and Pediatric Intensive Care), University of Arkansas for Medical Sciences, Arkansas Children's Hospital, 1 Children's Way, Slot 512-1, Little Rock, AR, 72202, USA.
Insights
This study found that post-operative hospital length of stay (PH-LOS) for infant coarctation of the aorta (COA) repair is increasing. Prematurity and other congenital anomalies are key risk factors for longer stays and higher mortality.
Area of Science:
- Pediatric Cardiology
- Congenital Heart Disease
- Surgical Outcomes
Background:
- Coarctation of the aorta (COA) is a common congenital heart defect.
- Infant surgical repair of isolated COA typically has a low mortality rate.
- Understanding factors influencing post-operative hospital length of stay (PH-LOS) is crucial for resource management and patient care.
Purpose of the Study:
- To assess trends in PH-LOS and NICU hospital length of stay (NICU-LOS) for isolated COA repair in infants.
- To identify independent risk factors associated with prolonged PH-LOS and in-hospital mortality.
- To provide the largest published systematic assessment of PH-LOS in this patient population.
Main Methods:
- Retrospective study using data from the Pediatric Health Information System (PHIS) database.
- Included pediatric patients (≤3 months) undergoing surgical repair of isolated COA between 2004 and 2018.
- Analyzed demographics, comorbidities, procedures, and outcomes, comparing different time periods.
Main Results:
- A total of 5354 patients were included.
- Observed an increasing trend in PH-LOS and NICU-LOS over the study period.
- Prematurity (<37 weeks gestation), congenital anomalies, and additional respiratory/abdominal surgeries were independent risk factors for longer PH-LOS and higher mortality.
Conclusions:
- This study represents the largest systematic assessment of PH-LOS in infants with isolated COA repair.
- Identified prematurity and other comorbidities as significant independent risk factors for increased PH-LOS.
- Highlights the need for further investigation into strategies to mitigate prolonged hospital stays in this vulnerable population.
Abstract:
Coarctation of the aorta is a relatively common congenital heart disease occurring in 0.4-0.6 per 1000 live births with a low mortality rate. This is a retrospective study, with data abstracted from the Pediatric Health Information System database (PHIS). The study sample included pediatric patients less than or equal to 3 months of age discharged from a PHIS participating hospital between January 1, 2004 and December 31, 2018 who underwent surgical repair of isolated COA. The primary outcome for the study was post-operative hospital length of stay (PH-LOS), and the secondary outcome was in-hospital mortality. Patient demographics, comorbidities, procedures, and outcomes were assessed for statistical differences between eras. A total of 5354 patients were included in the study. The study highlights an increasing trend in PH-LOS and NICU hospital length of stay (NICU-LOS) across the investigated eras. Prematurity (before 37 weeks gestation) was an independent risk factor associated with both longer post-operative length of the stay and higher mortality. In addition, congenital anomalies, respiratory and abdominal surgeries have a significant impact on the post-operative hospital stay. In conclusion, this study is the largest published systematic assessment of PH-LOS in patients with isolated COA repair during infancy to date and identifies independent risk factors of increased PH-LOS.
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