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Author Spotlight: Genetic Profiling for Fluorouracil Response in Gastric Cancer
Published on: May 10, 2024
Advances in Systemic Therapy for Gastric Cancer
Andrew Hsu1, Alexander G Raufi1
1The Warren Alpert Medical School of Brown University, Lifespan Cancer Institute, Rhode Island Hospital/The Miriam Hospital, 164 Summit Avenue, Fain Building, Third Floor, Providence, RI 02906, USA.
Abstract:
Gastric cancer represents a major global health problem. Approximately half of patients are diagnosed with early stage disease and surgical resection is potentially curative. The addition of combination chemotherapy, with or without radiotherapy, to surgery has been shown to improve outcomes. In metastatic disease, combination chemotherapy in the form of 2- or 3-drug regimens has been used. The aim of this chapter is to summarize currently approved systemic treatment options for gastric cancer and to highlight several promising treatments currently under investigation.
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