Performance of Primary Angioplasty for STEMI during the COVID-19 Outbreak

Surya Dharma1, Iwan Dakota2, Isman Firdaus2

  • 1Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia, Indonesian Cardiovascular Research Center, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia.

Insights

During the COVID-19 outbreak, ST-segment elevation myocardial infarction (STEMI) cases declined, impacting primary angioplasty performance. While door-to-device times increased, key outcomes like TIMI 3 flow and in-hospital mortality remained similar, supporting angioplasty as standard care.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Public Health

Background:

  • The COVID-19 pandemic led to concerns about the impact on acute myocardial infarction care.
  • Declining ST-segment elevation myocardial infarction (STEMI) admissions raised questions about primary angioplasty effectiveness during the outbreak.

Purpose of the Study:

  • To assess primary angioplasty performance for STEMI patients during the COVID-19 outbreak compared to the pre-outbreak period.
  • To evaluate door-to-device (DTD) times and thrombolysis in myocardial infarction (TIMI) flow outcomes.

Main Methods:

  • A comparative study analyzing STEMI admissions and primary angioplasty data from March 1 to May 31, 2020 (outbreak) versus March 1 to May 31, 2019 (pre-outbreak).
  • Key metrics included STEMI admission rates, DTD time, symptom onset-to-admission time, radial access uptake, infarct-related artery, TIMI flow, and in-hospital mortality.

Main Results:

  • STEMI admissions decreased by 44% during the COVID-19 outbreak.
  • Median DTD time and total ischemia time were significantly longer during the outbreak (104 vs. 81 minutes, p < 0.001).
  • Final TIMI 3 flow achievement (87.1% vs. 87.2%) and in-hospital mortality (5.7% vs. 7.8%) were similar between the two periods.

Conclusions:

  • Despite longer DTD times during the COVID-19 outbreak, primary angioplasty maintained similar procedural success and patient outcomes.
  • Primary angioplasty remains the recommended standard of care for STEMI management, even during public health emergencies like the COVID-19 pandemic.

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