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Published on: August 6, 2021
Photopigment Bleaching Phenomenon on Fluorescein Angiography in a Patient with Impending Central Retinal Vein
Narges Hassanpoor1,2, Ahmad Mirshahi1, Mohammad Reza Niyousha2
1Retina & Vitreous Service, Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Purpose:
To present the second case of photopigment bleaching phenomenon in fluorescein angiography (FA) and the first case of this phenomenon due to impending central retinal vein occlusion (CRVO).
Case Report:
A 32-year-old healthy female noticed blurred vision in her right eye one day before presentation. Despite the 20/20 visual acuity at presentation, mild increased retinal vascular tortuosity and unilateral photopigment bleaching phenomenon in FA was observed in the right eye. Three weeks later, she developed a complete CRVO with visual acuity reduction to 20/40 that responded well to the intravitreal injection of aflibercept.
Conclusion:
Impending CRVO can cause unilateral photopigment bleaching phenomenon in FA that may be due to retinal ischemia.

