Related Experiment Video
Updated: Nov 4, 2025

Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia
Published on: May 26, 2023
Role of Anaesthetic Choice in Improving Outcome after Cardiac Surgery
Clinical Background:
Volatile anaesthetics (VAs) have been shown to protect cardiomyocytes against ischaemia and reperfusion injury in cardiac surgery.
Clinical Problems:
VAs have been shown in multiple trials and meta-analyses to be associated with better outcomes when compared to intravenous anaesthesia in cardiac surgery. However, recent data from a large randomised controlled trial do not confirm the superiority of VA as compared to total intravenous anaesthesia in this population.
Review Objectives:
This mini review presents the VA cardioprotective effects, their clinical use in cardiac surgery and the most recent evidence that compares VA to intravenous anaesthesia for reducing perioperative morbidity. At present, there is no clear superiority of VA over intravenous anaesthesia in improving the outcome after cardiac surgery.
Related Concept Videos
General Anesthesia: Overview
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
Parenteral Anesthetics: Overview
Stages of General Anesthesia
Local Anesthetics: Pharmacokinetics
Local Anesthetics: Clinical Application as Spinal Anesthesia
Cardiomyopathy VII: Pre and Post Operative Nursing Management

