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Updated: Nov 4, 2025

Interactome-Seq: A Protocol for Domainome Library Construction, Validation and Selection by Phage Display and Next Generation Sequencing
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LCD-Composer: an intuitive, composition-centric method enabling the identification and detailed functional mapping of

Sean M Cascarina1, David C King1, Erin Osborne Nishimura1

  • 1Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523, USA.

NAR Genomics and Bioinformatics
|May 31, 2021
PubMed
Summary

We developed LCD-Composer, a new tool to directly identify protein Low Complexity Domains (LCDs) by analyzing amino acid composition. This method offers a more fundamental approach to understanding protein complexity across all life forms.

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