Genomic divergence during artificial selection by feed conversion ratio in Pekin ducks

Area of Science:

• Animal Genetics
• Quantitative Trait Genomics
• Poultry Science

Background:

• Feed conversion ratio (FCR) is crucial for Pekin duck production efficiency.
• Understanding the genetic basis of FCR is complex and vital for breeding programs.

Purpose of the Study:

• To investigate the genetic mechanisms underlying feed conversion efficiency in Pekin ducks.
• To identify candidate genes associated with improved FCR in an artificially selected line.

Main Methods:

• Whole-genome resequencing of an artificial selection (S) line and a natural (Z7) population.
• Analysis of population genetics statistics (FST, θπ, XP-EHH) to detect selection signatures.
• Integration of multiple methods to identify overlapping candidate genes.

Main Results:

• The artificial selection line showed significantly lower FCR compared to the natural population.
• Identification of 450-479 candidate genes and 1,933-1,964 candidate divergent regions (CDRs).
• 30 overlapping candidate genes were identified, including KCNQ1 and ADCY7.

Conclusions:

• Variants in KCNQ1 and ADCY7, involved in pancreatic secretion, are potential molecular markers for high feed efficiency.
• These findings provide insights into the genetic control of FCR in Pekin ducks.
• This research can aid in developing more efficient duck breeding strategies.