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Development and Validation of a Comprehensive Genomics Knowledge Scale.
Michael D Linderman1, Sabrina A Suckiel2, Nathan Thompson3
1Department of Computer Science, Middlebury College, Middlebury, Vermont, USA.
Public Health Genomics
|May 31, 2021
Summary
A new 26-item GKnowM scale accurately measures genomics knowledge for informed decisions and effective education. This tool is crucial for assessing population genomic literacy and the impact of educational programs.
Area of Science:
- Genomics
- Psychometrics
- Health Literacy
Background:
- Genomic testing is widespread across clinical, research, and commercial sectors.
- Genomic literacy is essential for the effective use of genomic testing.
- Validated tools are needed to assess genomics knowledge in diverse populations.
Purpose of the Study:
- To develop and validate the GKnowM Genomics Knowledge Scale.
- To create a reliable measure for informed decision-making regarding genomic testing.
- To assess knowledge relevant to genomic technologies and civic engagement.
Main Methods:
- Developed a 30-item draft scale, administered to 2,405 participants.
- Performed psychometric calibration and validation using classical test theory and IRT.
- Evaluated suitability for computerized adaptive testing (CAT).
Main Results:
- The final 26-item GKnowM scale demonstrated strong internal consistency (α = 0.85).
- The scale showed good validity, correlating with existing measures and differentiating knowledge levels.
- The item bank is suitable for CAT, reducing the number of items administered.
Conclusions:
- GKnowM is a validated, broadly relevant measure for assessing genomics knowledge.
- The scale can evaluate population genomic literacy and educational intervention effectiveness.
- GKnowM supports informed decision-making and participation in genomic healthcare.
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