Related Experiment Video
Updated: Nov 3, 2025

Simultaneous Brightfield, Fluorescence, and Optical Coherence Tomographic Imaging of Contracting Cardiac Trabeculae Ex Vivo
Published on: October 2, 2021
Intensity correlation OCT is a classical mimic of quantum OCT providing up to twofold resolution improvement
Sylwia M Kolenderska1, Piotr Kolenderski2
1The Dodd-Walls Centre for Photonic and Quantum Technologies, Department of Physics, University of Auckland, Auckland, 1010, New Zealand. skol745@aucklanduni.ac.nz.
Abstract:
Quantum Optical Coherence Tomography (Q-OCT) uses quantum properties of light to provide several advantages over its classical counterpart, OCT: it achieves a twice better axial resolution with the same spectral bandwidth and it is immune to even orders of dispersion. Since these features are very sought-after in OCT imaging, many hardware and software techniques have been created to mimic the quantum behaviour of light and achieve these features using traditional OCT systems. The most recent, purely algorithmic scheme-an improved version of Intensity Correlation Spectral Domain OCT named ICA-SD-OCT-showed even-order dispersion cancellation and reduction of artefacts. The true capabilities of this method were unfortunately severely undermined, both in terms of its relation to Q-OCT and its main performance parameters. In this work, we provide experimental demonstrations as well as numerical and analytical arguments to show that ICA-SD-OCT is a true classical equivalent of Q-OCT, more specifically its Fourier domain version, and therefore it enables a true two-fold axial resolution improvement. We believe that clarification of all the misconceptions about this very promising algorithm will highlight the great value of this method for OCT and consequently lead to its practical applications for resolution- and quality-enhanced OCT imaging.
Related Concept Videos
Phase Contrast and Differential Interference Contrast Microscopy
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
Imaging Biological Samples with Optical Microscopy
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
Electron Microscope Tomography and Single-particle Reconstruction
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
Total Internal Reflection Fluorescence Microscopy
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Super-resolution Fluorescence Microscopy

