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Biological significance of HLA-A,B,C expression in neuroblastoma and related cell lines
1Children's Cancer Research Center, Children's Hospital of Philadelphia, PA 19104.
Progress in Clinical and Biological Research
|January 1, 1988
Abstract:
In these studies, strong HLA-A,B,C or b2-m expression was not detected in any stage of development of normal neurons. These included regenerating cells of the olfactory epithelium, developing neural tissue in the mouse embryo, and normal adult brain. Nor was an obligatory role for HLA-A,B,C or b2-m revealed by in vitro analysis of a growing neuroblastoma cell line.
