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Stabilization of Azapeptides by Namide···H-Namide Hydrogen Bonds

Kalpita Baruah1, Biswajit Sahariah2, Sushil S Sakpal3,4

  • 1Department of Chemistry, School of Natural Sciences, Shiv Nadar University, Dadri, Uttar Pradesh 201314, India.

Organic Letters
|June 1, 2021
PubMed

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Direct alkylation of ammonia produces polyalkylated amines, along with a quaternary ammonium salt. To exclusively prepare primary amines, the azide synthesis method can be used.
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Acid-catalyzed hydrolysis:
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