Related Experiment Video
Updated: Nov 3, 2025

Synthesis of In37P20O2CR51 Clusters and Their Conversion to InP Quantum Dots
Published on: May 7, 2019
Chiral Inversion and Conservation of Clusters: A Case Study of Racemic Ag32Cu12 Nanocluster
Jinsong Chai1,2, Sha Yang2, Tao Chen1
1Department of Chemistry and Centre for Atomic Engineering of Advanced Materials, Anhui Province Key Laboratory of Chemistry for Inorganic/Organic Hybrid Functionalized Materials, Anhui University, Hefei, Anhui 230601, China.
Abstract:
Chiral metal nanoclusters have been widely reported, but their separation and optical stabilization remain challenging. We used a deracemization strategy to accomplish the enantioseparation of a racemic mixture of [Ag32Cu12(CH3COO)12(SAdm)12(P(CH3OPh)3)4] (M44) in a yield exceeding 50%, forming two optically active [Ag32Cu12(R/S-Cl(CH3)CHCOO)12(SAdm)12(P(CH3OPh)3)4] (R/S-M44') enantiomers. The optical activity of these products was conserved after exchange of the chiral carboxyl ligands with achiral ligand (Br-), to give two additional optically active nanoclusters R/S-[Ag28Cu16Br12(SAdm)12(P(CH3OPh)3)4] (R/S(Br)-M44). The crystal structures of the above nanoclusters were determined by single-crystal X-ray crystallography. Based on these structures, the chiral transformation and conservation are mapped out.
More Related Videos
06:35Construction and Systematical Symmetric Studies of a Series of Supramolecular Clusters with Binary or Ternary Ammonium Triphenylacetates
Published on: February 15, 2016
10:17Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
Published on: February 7, 2019
Related Concept Videos
SN1 Reaction: Stereochemistry
In the first step of an SN1 reaction, the bond between the electrophilic carbon and the leaving group ionizes to generate the carbocation intermediate. The second step of the mechanism is the nucleophilic attack.
In the formed carbocation, the positively charged carbon is sp2 hybridized with a trigonal planar geometry. As all the three substituents lie on the same plane, a plane of symmetry for the...
Chirality at Nitrogen, Phosphorus, and Sulfur
A consequence of chirality is the need for enantiomeric resolution. While this is theoretically possible for all...
Prochirality
Stereoisomerism of Cyclic Compounds
Racemic Mixtures and the Resolution of Enantiomers
Naming Enantiomers