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Updated: Nov 3, 2025
Hand-held Clinical Photoacoustic Imaging System for Real-time Non-invasive Small Animal Imaging
Published on: October 16, 2017
Technical Note: Compact thermoacoustic imaging system based on a low-cost and miniaturized microwave generator for
Lin Huang1,2,3, Zhu Zheng1,4, Zihui Chi1
1School of optoelectric Engineering, Chongqing University of Posts and Telecommunications, Chongqing, 400065, China.
Purpose:
Most of existing thermoacoustic imaging (TAI) studies generally utilized a linear modulator-based high peak power magnetron generator (MG) for efficient TA signal excitation. However, a linear modulator-based MG is bulky and expensive. Here we present a low-cost and compact thermoacoustic imaging (TAI) system based on a miniaturized MG.
Methods:
The MG is based on solid-state modulator and operates at 3.05 ± 0.025 GHz, with a peak power of up to 60 kW and adjustable pulse duration from 70 to 600 ns. The dimensions and weight of this MG are 350 × 210 × 70 mm3 (Width × Length × Height) and 7.5 kg, respectively.
Results:
The spatial resolution of the miniaturized MG-based TAI system is determined to be from 0.3 to 1.4 mm using controlled phantom experiments. The system is further evaluated using in vivo experiments where the finger joints and vasculature in the forearm and opisthenar of human participants are successfully imaged.
Conclusions:
This study suggests that the miniaturized MG based TAI systems can be used for in vivo joint and vascular imaging with multiscale resolutions (0.3-1.4 mm).
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