[Correlations between clinico-psychiatric findings and the dexamethasone suppression test in depression]

A study on 50 patients with endogenous and non-endogenous depression yielded a sensitivity of 64% and a specificity of 77% for the dexamethasone suppression test (DST). Endogenous depressive patients recovering from depression within one week mostly showed sufficient cortisol suppression. "Loss of feelings" was associated more frequently with cortisol nonsuppression, while a certain relationship between psychogenic induction of the present depressive episode and adequate suppression could be demonstrated. In conclusion, the diagnostic utility of the DST is of minor importance. However, in certain cases the DST could be recommended as a predictor of clinical course.