Cholinergic REM sleep induction by arecoline in normal subjects: relation to thyroid function
Related Experiment Videos
M Keshavan1, S Dubé, J Grabowski
1Department of Psychiatry, Wayne State University, Detroit, MI.
Psychiatry Research
|June 1, 1988
Abstract:
Serum thyroid hormones and the speed of rapid eye movement (REM) sleep induction by the central muscarinic agonist arecoline were measured in 21 normal volunteers. The arecoline-REM induction latencies had a modestly significant negative correlation with free thyroxine index. This finding is discussed in the light of observations in animal studies that thyroid hormones stimulate central cholinergic neuronal function.