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ARCGHR Neurons Regulate Muscle Glucose Uptake.

Juliana Bezerra Medeiros de Lima1, Lucas Kniess Debarba1, Alan C Rupp2

  • 1Department of Biological Sciences, Integrative Biosciences Center (IBio), Wayne State University, Detroit, MI 48202, USA.

Cells
|June 2, 2021
PubMed
Summary

Growth hormone receptor (GHR) neurons in the hypothalamus arcuate nucleus (ARC) regulate feeding and glucose metabolism. Activating these ARC GHR+ neurons enhances glucose utilization and improves insulin sensitivity, particularly in skeletal muscle.

Keywords:
arcuate nucleus of the hypothalamusenergy homeostasisglucose metabolismgrowth hormone receptor

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