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Stem Cell Therapy for Modulating Neuroinflammation in Neuropathic Pain
Hari Prasad Joshi1,2, Hyun-Jung Jo3, Yong-Ho Kim3
1Department of Neurosurgery, School of Medicine, CHA University, CHA Bundang Medical Center, Seongnam-si 13496, Gyeonggi-do, Korea.
International Journal of Molecular Sciences
|June 2, 2021
Summary
Neuropathic pain (NP) is a challenging condition. Stem cell therapy shows promise as a novel treatment, offering potential neuroprotective effects and new therapeutic avenues for patients.
Area of Science:
- Neuroscience
- Regenerative Medicine
- Pain Research
Background:
- Neuropathic pain (NP) is a complex, chronic pain condition resulting from somatosensory system damage.
- Current treatments offer limited efficacy and safety for many patients.
- Novel therapeutic strategies are urgently needed.
Purpose of the Study:
- To review the current understanding of neuropathic pain.
- To explore the potential of stem cell therapy for NP treatment.
- To summarize stem cell mechanisms and translational research in NP.
Main Methods:
- Literature search using PubMed.
- Review of preclinical studies on stem cells for NP.
- Analysis of stem cell mechanisms, including neuromodulation.
Main Results:
- Stem cell therapy demonstrates significant potential for treating NP.
- Stem cells exhibit neuroprotective effects relevant to NP.
- Translational research highlights the viability of stem cell-based NP treatments.
Conclusions:
- Stem cell therapy represents a promising novel approach for managing neuropathic pain.
- Further research and clinical translation are warranted to harness the full therapeutic potential of stem cells for NP.
