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Successful long term oral zinc in florid Wilson's disease: a case report
U Kaur1, P Bambery, S R Bhushnurmath
1Department of Experimental Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Abstract:
We describe the clinical course of a patient with florid, predominantly neurological, Wilson's disease who developed serious toxic effects of d-penicillamine therapy but responded well to long term oral zinc sulphate. A congenital portosystemic shunt has decompressed the portal bed adequately to prevent the development of varices. We also documented the return to normal of a grossly abnormal pancreolauryl test after withdrawal of zinc.