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Pre-Sleep Casein Supplementation, Metabolism, and Appetite: A Systematic Review.
Justin Dela Cruz1, David Kahan1
1School of Exercise and Nutritional Sciences, San Diego State University, San Diego, CA 92182, USA.
Nutrients
|June 2, 2021
Summary
Pre-sleep casein protein supplementation shows limited effects on metabolism and appetite in healthy and overweight individuals. More research is needed to fully understand the impact of this nutritional strategy.
Area of Science:
- Sports Nutrition
- Nutritional Biochemistry
- Metabolic Health
Background:
- Nighttime is typically a catabolic period, influencing metabolic shifts.
- Pre-sleep casein protein supplementation is a novel strategy in sports nutrition.
- Existing research suggests benefits for skeletal muscle adaptation to resistance training.
Purpose of the Study:
- To systematically review the effects of pre-sleep casein protein on energy expenditure, lipolysis, appetite, and food intake.
- To investigate these effects in both healthy and overweight or obese individuals.
Main Methods:
- Systematic review conducted following PRISMA guidelines.
- Searches performed in CINAHL, Cochrane, and SPORTDiscus databases in March 2021.
- 11 studies met the inclusion criteria for analysis.
Main Results:
- Limited evidence suggests pre-sleep casein protein (24-48 g) has minimal impact on energy expenditure and appetite.
- No significant effects observed on lipolysis or overall food intake in the reviewed studies.
- Data are currently limited, indicating a need for further investigation.
Conclusions:
- Pre-sleep casein protein supplementation appears to have negligible effects on metabolic parameters and appetite.
- Current evidence is insufficient to draw definitive conclusions.
- Further research is warranted to clarify the role of pre-sleep casein protein in metabolic regulation and appetite control.
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