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Updated: Nov 3, 2025

Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
Anthropometric Development in Children: Possible Changes in Body Mass, Basal Metabolic Rate and Inflammatory Status
Roxana Maria Martin-Hadmaș1, Ștefan Adrian Martin2, Adela Romonți1
1Department of Community Nutrition and Food Safety, "George Emil Palade" University of Medicine, Pharmacy, Science and Technology from Târgu Mureș, Gheorghe Marinescu 38, 540139 Mureș, Romania.
Insights
This study found that children's skinfold thickness is linked to inflammation markers like IL-6 and IL-8. Body weight changes also affected cholesterol and triglycerides, highlighting connections between body composition, inflammation, and metabolic health in children.
Area of Science:
- Pediatric Nutrition
- Biochemistry
- Public Health
Background:
- Global public health initiatives address childhood malnutrition through dietary pattern analysis.
- Research aims to understand anthropometric changes and their relation to dietary intake.
- This study investigates inflammatory status in relation to anthropometric changes and energy intake in children.
Purpose of the Study:
- To examine the relationship between inflammatory markers (IL-6, IL-8) and anthropometric measurements in children.
- To assess the impact of anthropometric changes on metabolic markers like cholesterol and triglycerides.
- To explore the connection between energy intake, inflammation, and body composition.
Main Methods:
- Analyzed serum IL-6 and IL-8 levels in 160 healthy children (6-12 years old).
- Measured cholesterol, triglycerides, total proteins, creatinine, Resting Metabolic Rate (RMR), and food intake.
- Utilized skinfold measurements and anthropometric indices (weight-for-age, height-for-age).
Main Results:
- Interleukin-6 (IL-6) levels correlated with skinfold thickness.
- Changes in skinfolds were significantly associated with total proteins and triglycerides.
- Weight-for-age and height-for-age correlated with skinfold values.
- Basal Metabolic Rate (BMR) measurements indicated significant changes in carbohydrate metabolism linked to IL-6 and respiratory quotient (RQ).
Conclusions:
- Skinfold thickness is significantly correlated with IL-6 and IL-8 levels in children.
- Changes in body weight were associated with alterations in serum cholesterol and triglycerides.
- Total proteins and creatinine levels did not show significant changes in relation to body weight changes.
Abstract:
(1) Background: Worldwide, public health policies focus on studying dietary patterns and the related anthropometric changes in children. Their aim is to improve the measures meant to reduce global malnutrition rates. Our goal was to study the main changes in the inflammatory status related to anthropometric changes and total daily energy intake. (2) Methods: We tested the study hypothesis by analyzing serum IL-6 and IL-8 levels, cholesterol and triglycerides values, as well as total proteins and creatinine levels, RMR, and food journals in a sample of 160 healthy subjects aged between 6 and 12 years old. (3) Results: IL-6 was correlated with the skinfold values. Changes in the skinfolds were significantly correlated with total proteins and triglycerides. Both weight for age and height for age were related to the skinfold values. Through the BMR measurements, peak carbohydrate metabolism changed significantly based upon IL-6 values, which were significantly correlated with the respiratory coefficient values. Based on the basal metabolic rate, an increased IL-8 ratio was related to the RQ value. (4) Conclusions: Skinfolds have been significantly correlated with IL-6 and IL-8 levels. With changes in body weight, we encountered differences in both serum cholesterol and serum triglycerides values, unlike total proteins and creatinine, which failed to change.
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