Related Experiment Video
Updated: Nov 3, 2025

Generation of Multicellular Human Primary Endometrial Organoids
Published on: October 4, 2019
Endometrial Perivascular Progenitor Cells and Uterus Regeneration
Shiyuan Li1,2,3, Lijun Ding1,2,3,4
1Center for Reproductive Medicine, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008, China.
Abstract:
Ovarian steroid-regulated cyclical regeneration of the endometrium is crucial for endometrial receptivity and embryo implantation, and it is dependent on the dynamic remodeling of the endometrial vasculature. Perivascular cells, including pericytes surrounding capillaries and microvessels and adventitial cells located in the outermost layer of large vessels, show properties of mesenchymal stem cells, and they are thus promising candidates for uterine regeneration. In this review, we discuss the structure and functions of the endometrial blood vasculature and their roles in endometrial regeneration, the main biomarkers and characteristics of perivascular cells in the endometrium, and stem cell-based angiogenetic therapy for Asherman's syndrome.
Related Concept Videos
Multipotency of Hematopoietic Stem Cells
Proliferative Phase
Notably, the stratum basale, the basal layer of the endometrium, including the basal parts of the uterine glands, remains unaffected by menstruation. Stem cells in this layer undergo mitosis, regenerating the stratum functionalis and thickening the...
Mesenchymal Stem Cells
Liver Regeneration
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are...
Source And Potency Of Stem Cells
Differentiation of Common Myeloid Progenitor Cells

