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Natural Products in the Prevention of Metabolic Diseases: Lessons Learned from the 20th KAST Frontier Scientists

Seung J Baek1, Bruce D Hammock2, In-Koo Hwang1

  • 1College of Veterinary Medicine, Seoul National University, Seoul 08826, Korea.

Nutrients
|June 2, 2021
PubMed

Insights

Natural products offer antioxidant and anti-inflammatory properties crucial for preventing and treating metabolic diseases like cancer and obesity. Advanced research explores their chemical identification, mechanisms, and enhanced delivery via nanotechnology.

Area of Science:

  • Biochemistry
  • Nanotechnology
  • Preventive Medicine

Background:

  • Metabolic and chronic diseases, including cancer and obesity, have risen sharply in the 21st century.
  • Inflammation and oxidative stress are identified as major underlying causes of these diseases.
  • Natural products possess inherent antioxidant and anti-inflammatory properties, making them promising therapeutic agents.

Purpose of the Study:

  • To review current knowledge on the role of natural products in preventing and treating metabolic diseases.
  • To summarize recent research on bioactive compounds, nanoparticles, and disease prevention.
  • To highlight advancements in chemical identification, mechanism of action, and bioavailability enhancement of natural products.

Main Methods:

  • Review of presentations from the 20th Frontier Scientists Workshop.
  • Discussion of advanced analytical techniques for chemical identification.
  • Exploration of nanotechnology applications for enhancing bioavailability and bioactivity.

Main Results:

  • Natural products are effective therapeutic agents due to their antioxidant and anti-inflammatory properties.
  • Research is expanding into chemical identification, mechanism of action studies, and food fortification.
  • Nanotechnology offers methods to enhance the bioavailability and bioactivity of natural compounds.

Conclusions:

  • Natural products play a significant role in the prevention and treatment of metabolic diseases.
  • Continued research into bioactive compounds and nanotechnology is vital for disease prevention.
  • The integration of natural products with advanced technologies holds promise for future therapeutics.
Keywords:
aginganti-inflammationantioxidantsbioactive food componentscancerinflammation-related diseasesnanoparticlesnatural productsobesity

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