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Hypoglycin A in Cow's Milk-A Pilot Study.

Mandy Bochnia¹, Jörg Ziegler², Maren Glatter¹

¹Institute of Agricultural and Nutritional Sciences, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany.

|June 2, 2021

Summary

This summary is machine-generated.

Hypoglycin A (HGA), a toxin found in sycamore maple trees, can transfer into dairy cow milk. Measurable HGA concentrations were detected in milk from cows grazing near these trees.

Keywords:

carry-over hypoglycin A intoxication raw milk transfer

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Area of Science:

Veterinary Toxicology
Food Safety
Environmental Health

Background:

Hypoglycin A (HGA) is a toxin found in soapberry fruits and sycamore maple trees.
HGA can cause severe health issues in humans and animals, including Jamaican vomiting sickness and atypical myopathy.
Previous studies have detected HGA in mare's milk and deer offal, suggesting potential transfer into food products.

Purpose of the Study:

To investigate the potential transfer of Hypoglycin A (HGA) into bulk raw milk from dairy cows.
To determine if HGA is present in milk from cows grazing in pastures containing sycamore maple trees.

Main Methods:

Bulk raw milk samples were collected from four dairy farms.
Milk samples were analyzed for HGA concentrations using Liquid Chromatography-Electrospray Ionization-Tandem Mass Spectrometry (LC-ESI-MS/MS).
Farm No. 1 had a sycamore maple tree on its pasture, while other farms did not.

Main Results:

Measurable concentrations of HGA (120 and 489 nmol/L) were detected only in milk samples from Farm No. 1.
HGA concentrations in the milk were low and highly variable.
The findings indicate that ingested HGA can be transferred into milk.

Conclusions:

The study provides evidence for the transfer of Hypoglycin A from ingested sources into dairy cow milk.
Further research, including carry-over studies and analysis of toxin stability during milk processing, is necessary for a comprehensive safety assessment.