Diagnosis and Treatment of Intracardiac Thrombus

Murti Patel1, Xin Wei2, Kylie Weigel3

  • 1Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA.

Insights

Intracardiac thrombi are common, but evidence-based guidance is limited. This review covers prevalence, diagnosis, and treatment for left atrial appendage, CIED lead, bioprosthetic aortic valve, and left ventricular thrombi.

Area of Science:

  • Cardiology
  • Thrombosis Research

Background:

  • Intracardiac thrombi are frequently encountered in clinical practice.
  • Limited evidence-based guidance exists for managing patients with intracardiac thrombi.

Purpose of the Study:

  • To review current knowledge on intracardiac thrombus.
  • To focus on four specific thrombus types with recent clinical shifts: left atrial appendage, cardiac implantable electronic device lead, bioprosthetic aortic valve, and left ventricular thrombus.

Main Methods:

  • Literature review summarizing prevalence, diagnostic strategies, clinical relevance, and treatment options.
  • Focus on recent research impacting clinical understanding and treatment decisions.

Main Results:

  • The review synthesizes existing data on various intracardiac thrombi.
  • Highlights specific findings related to the four focused thrombus types.

Conclusions:

  • Further high-quality research, including prospective and randomized trials, is necessary.
  • Improved evidence is needed to establish best practices for intracardiac thrombus management.

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