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Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Open Angle Glaucoma: Treatment01:27

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Related Experiment Video

Updated: Nov 3, 2025

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
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Complete and early vitrectomy for endophthalmitis.

Robert E Morris1,2, Ferenc Kuhn1,2,3,4

  • 1Retina Specialists of Alabama, Birmingham, AL, USA.

European Journal of Ophthalmology
|June 2, 2021
PubMed
Summary
This summary is machine-generated.

Complete and Early Vitrectomy for Endophthalmitis (CEVE) offers superior outcomes for Acute Post-Cataract Endophthalmitis (APCE). This approach restored vision in 79% of cases, significantly outperforming previous study results.

Keywords:
APCEEndophthalmitisTAPVIT EVSpostcataract endophthalmitistap and injectvitrectomy

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Area of Science:

  • Ophthalmology
  • Retinal Surgery
  • Infectious Disease

Background:

  • A ten-year retrospective analysis (2007-2017) of Acute Post-Cataract Endophthalmitis (APCE) treatment outcomes at Retina Specialists of Alabama.
  • Focus on the efficacy of Complete and Early Vitrectomy for Endophthalmitis (CEVE) as an initial treatment strategy.

Discussion:

  • Comparison of CEVE outcomes with historical data from the Endophthalmitis Vitrectomy Study.
  • Analysis of visual acuity restoration rates in APCE patients treated with CEVE.

Key Insights:

  • CEVE achieved a 79% restoration of visual acuity (≥ 20/40) in APCE cases.
  • This success rate significantly exceeds the 53% reported in the Endophthalmitis Vitrectomy Study.
  • 77.4% of analyzed eyes received CEVE as their primary treatment.

Outlook:

  • CEVE is recommended as the primary treatment for APCE when vitreous opacity obscures fundus view.
  • Further research may explore long-term outcomes and refine CEVE protocols.
  • Potential for improved patient outcomes in post-cataract endophthalmitis management.