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Horizontal Guided Bone Regeneration Using a Dehydrated Amnion/Chorion Membrane: A Case Report
Summary
This study shows that a dehydrated amnion/chorion membrane (dHACM) effectively regenerates horizontal bone volume. This allows for dental implant placement in previously deficient jaw areas, demonstrating a novel biomaterial
Area of Science:
- Dental surgery
- Biomaterials science
- Regenerative medicine
Background:
- Guided bone regeneration (GBR) is crucial for dental implantology.
- Alveolar ridge deficiencies often preclude implant placement.
- Novel biomaterials are needed to enhance GBR efficacy.
Observation:
- A dehydrated amnion/chorion membrane (dHACM) was used for horizontal GBR.
- The membrane was combined with autogenous bone and mineralized bovine bone.
- The procedure was performed in the anterior maxilla.
Findings:
- Significant horizontal bone width increase was observed 8 months post-surgery.
- Endosseous dental implants achieved excellent primary stability.
- Implants were successfully restored with a screw-retained bridge prosthesis.
Implications:
- This novel dHACM approach facilitates dental implant placement in deficient ridges.
- dHACM shows excellent clinical potential as a biomaterial for horizontal GBR.
- This represents the first report of dHACM for horizontal GBR with subsequent implant restoration.

