Long-coronavirus disease among people living with HIV in western India: An observational study

Sanjay Pujari1, Sunil Gaikwad1, Abhishek Chitalikar1

  • 1Institute of Infectious Diseases, Pune, India.

Insights

Long-COVID is prevalent in people living with HIV (PLHIV), especially after moderate-severe COVID-19. Integrating long-COVID care into HIV clinics is crucial for this population.

Area of Science:

  • Infectious Diseases
  • Public Health
  • HIV Medicine

Background:

  • Long-COVID presents a growing health challenge for individuals recovering from COVID-19.
  • Limited data exists on the prevalence, characteristics, and risk factors of long-COVID among people living with HIV (PLHIV).

Purpose of the Study:

  • To investigate the prevalence and identify risk factors for long-COVID in people living with HIV.
  • To understand the clinical presentation and symptom duration of long-COVID in this specific cohort.

Main Methods:

  • A prospective, observational study conducted at a tertiary HIV clinic in India.
  • Screening of 94 PLHIV using a questionnaire for long-COVID symptoms (present >30 days post-illness onset).
  • Logistic regression analysis to determine risk factors associated with long-COVID development.

Main Results:

  • The prevalence of long-COVID among PLHIV was 43.6%.
  • Moderate-to-severe acute COVID-19 illness was a significant risk factor (aOR 4.7, p=0.016).
  • Common symptoms included cough and fatigue; persistent symptoms were noted in 10.6% of cases.

Conclusions:

  • Long-COVID is common in PLHIV, particularly those with moderate-to-severe COVID-19.
  • Integration of long-COVID diagnosis and care into antiretroviral therapy clinics is recommended for PLHIV.
Abstract

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