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Updated: Nov 3, 2025

Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System
Published on: May 24, 2017
Objective assessment of nasal resistance among electronic cigarette users
1Otorhinolaryngology Department, University of Malaya Medical Centre, Kuala Lumpur, Malaysia.
Background:
Electronic cigarettes have been a popular alternative to tobacco smoking. The effect of tobacco smoking on nasal airway resistance has been investigated before; however, the effect of the aerosol generated by electronic cigarettes is still unknown. This study aimed to evaluate the short-term effects of e-cigarettes on nasal airway resistance.
Methods:
Sixty-one participants were recruited into a vapers group and a control group. The vapers group was instructed to smoke for 5 minutes, and their nasal resistance was measured pre-procedure and at 1 and 5 minutes post-procedure. The results were compared between both groups.
Results:
Repeated measures analysis of variance demonstrated that vaping has no statistically significant effect on total nasal airway resistance.
Conclusion:
Although the differences between both groups were not statistically significant overall, the vapers group showed a reduction in nasal airway resistance in the short term.
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