Effects of Treatment Setting on Outcomes of Flexibly-Dosed Intensive Cognitive Behavioral Therapy for Pediatric OCD:
Robert R Selles1,2, Zainab Naqqash1,2, John R Best1,2,3
1British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada.
Insights
Intensive cognitive-behavioral therapy (CBT) effectively treats pediatric obsessive-compulsive disorder (OCD). Home-based treatment showed minor benefits for maintaining gains and patient comfort, though outcomes were similar to clinic-based care.
Area of Science:
- Child and Adolescent Psychiatry
- Behavioral Therapy
- Mental Health Treatment
Background:
- Optimizing outcomes for pediatric cognitive-behavioral therapy (CBT) is crucial.
- Individualized treatment approaches are needed to enhance efficacy.
- Pediatric obsessive-compulsive disorder (OCD) requires effective therapeutic interventions.
Purpose of the Study:
- To compare the efficacy of intensive CBT delivered in a hospital clinic versus a home-based setting for youth with OCD.
- To assess treatment satisfaction and utilization patterns of flexible-dose CBT.
- To evaluate OCD-related and secondary outcomes at multiple time points.
Main Methods:
- Randomized controlled trial comparing hospital-based intensive CBT (n=14) with home-based intensive CBT (n=12).
- Both groups received 3 initial 3-hour sessions, with optional additional sessions (Phase II).
- Outcomes including OCD severity, impairment, quality of life, and comorbid symptoms were assessed post-treatment and at 1- and 6-month follow-ups.
Main Results:
- High family satisfaction reported for both treatment settings.
- Significant improvements observed in OCD-related outcomes and moderate benefits in secondary domains.
- No statistically significant differences in primary outcomes between settings; home-based treatment showed slight advantages in gain maintenance and comfort.
Conclusions:
- Intensive CBT is an effective treatment for pediatric OCD, with flexible dosing based on patient needs.
- Home-based CBT offers comparable efficacy to clinic-based treatment, with potential advantages in specific areas.
- Further research into tailored delivery methods for pediatric OCD treatment is warranted.
Abstract:
Introduction: Optimizing individual outcomes of cognitive-behavioral therapy (CBT) remains a priority. Methods: Youth were randomized to receive intensive CBT at a hospital clinic (n = 14) or within their home (n = 12). Youth completed 3 × 3 h sessions (Phase I) and up to four additional 3-h sessions as desired/needed (Phase II). An independent evaluator assessed youth after Phase I, Phase II (when applicable), and at 1- and 6-months post-treatment. A range of OCD-related (e.g., severity, impairment) and secondary (e.g., quality of life, comorbid symptoms) outcomes were assessed. Results: Families' satisfaction with the treatment program was high. Of study completers (n = 22), five youth (23%) utilized no Phase II sessions and 9 (41%) utilized all four (Median Phase II sessions: 2.5). Large improvements in OCD-related outcomes and small-to-moderate benefits across secondary domains were observed. Statistically-significant differences in primary outcomes were not observed between settings; however, minor benefits for home-based treatment were observed (e.g., maintenance of gains, youth comfort with treatment). Discussion: Intensive CBT is an efficacious treatment for pediatric OCD. Families opted for differing doses based on their needs. Home-based treatment, while not substantially superior to hospital care, may offer some value, particularly when desired/relevant. Clinical Trial Registration: www.ClinicalTrials.gov; https://clinicaltrials.gov/ct2/show/NCT03672565, identifier: NCT03672565.
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