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Updated: Nov 3, 2025

A Bedside, Single Burr Hole Approach to Multimodality Monitoring in Severe Brain Injury
Published on: March 26, 2019
Intraparenchymal Neuromonitoring of Cerebral Fat Embolism Syndrome
Ryan Leo Hoiland1,2, Donald E Griesdale1,3,4, Peter Gooderham5
1Department of Anaesthesiology, Pharmacology and Therapeutics, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada.
Objectives:
We aimed to characterize the cerebrovascular physiology of cerebral fat embolism using invasive multimodal neuromonitoring.
Data Sources:
ICU, Vancouver General Hospital, Vancouver, BC, Canada.
Study Selection:
Case report.
Data Extraction:
Patient monitoring software (ICM+, Cambridge, United Kingdom), clinical records, and surgical records.
Data Synthesis:
None.
Conclusions:
Our integrated assessment of the cerebrovascular physiology of fat embolism syndrome provides a physiologic basis to investigate the importance of augmenting mean arterial pressure to optimize cerebral oxygen delivery for the mitigation of long-term neurologic ischemic sequelae of cerebral fat embolism.

