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Updated: Nov 3, 2025

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
Published on: April 23, 2019
Increased utilization of buprenorphine and methadone in 2018 compared to 2015 among Seattle-area persons who inject
Elisabeth Poorman1, Sara N Glick2, Jonathan K D Hiser1
1University of Washington, Division of General Internal Medicine, Department of Medicine, 325 9th Avenue, Seattle, WA 98104, USA.
Objective:
To describe utilization patterns of methadone and buprenorphine among persons who inject drugs (PWID) in the Seattle area in 2018, compared to 2015.
Methods:
Data from the 2018 National HIV Behavioral Surveillance (NHBS) system were used to compare the proportions of PWID reporting treatment with buprenorphine or methadone to survey responses in 2015. Temporal trends were assessed by calculating adjusted prevalence ratios (aPR) using Poisson regression.
Results:
The sample included 498 PWID, of whom 39.2% (95% CI: 34.8-43.6%) reported past-year treatment with methadone and 21.9% (95% CI: 18.3-25.8%) reported buprenorphine. Participants in 2018 were significantly more likely to report past year receipt of buprenorphine (aPR = 4.43, 95% CI: 2.81-7.01) or methadone (aPR = 1.38, 95% CI: 1.02-1.87) compared to 2015. Most buprenorphine treated participants (67.6%) reported that they had received buprenorphine through low-barrier, community, or nonprofit programs.
Conclusions:
Among PWID who use opioids in the Seattle area, methadone use increased 38%, and buprenorphine use more than quadrupled from 2015 to 2018. Approximately half of surveyed PWID who use opioids still reported no treatment with either medication, highlighting remaining treatment gaps.
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