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Updated: Nov 3, 2025

Assessing the Multiple Dimensions of Engagement to Characterize Learning: A Neurophysiological Perspective
Published on: July 1, 2015
Daniel S Pine1, Steven P Wise1, Elisabeth A Murray1
1Section on Development and Affective Neuroscience, Emotion and Development Branch (Pine), and Section on the Neurobiology of Learning and Memory, Laboratory of Neuropsychology (Murray), NIMH, Bethesda, Md.; Olschefskie Institute for the Neurobiology of Knowledge, Bethesda, Md. (Wise).
Human brain evolution, particularly expanded association areas and hippocampus, contributes to emotional disorders. Unique cognitive abilities like reliving past and imagining future events increase risks for stress and mood disorders.
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