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Updated: Nov 3, 2025

Rejection of Fluorescence Background in Resonance and Spontaneous Raman Microspectroscopy
Published on: May 18, 2011
Advancing Raman spectroscopy from research to clinic: Translational potential and challenges
Swati Tanwar1, Santosh Kumar Paidi1, Ram Prasad2
1Department of Mechanical Engineering, Johns Hopkins University, Baltimore, MD 21218, United States.
Abstract:
Raman spectroscopy has emerged as a non-invasive and versatile diagnostic technique due to its ability to provide molecule-specific information with ultrahigh sensitivity at near-physiological conditions. Despite exhibiting substantial potential, its translation from optical bench to clinical settings has been impacted by associated limitations. This perspective discusses recent clinical and biomedical applications of Raman spectroscopy and technological advancements that provide valuable insights and encouragement for resolving some of the most challenging hurdles.
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