A comparison of two pulp revascularization techniques using platelet-rich plasma and whole blood clot

The aim of this preliminary study was to compare outcomes of two regenerative endodontic protocols in necrotic teeth with open apices.

Forty teeth with open apices in patients with an age range of 15-54 were randomly distributed in two groups: group 1, with whole blood clot in the canal (n=20) and group 2, whole blood with Platelet rich plasma (PRP) in the canal (n=20). Clinical and radiological follow up assessments were undertaken over a period ranging from 6 months to one year. Radiographic Root Area (RRA) was measured using the freeware ImageJ. Statistical analysis was performed using the independent samples t test and the Chi-squared test, the significance level was set at p=0.05.

There was no difference in the percentage change in RRA between the PRP group and whole blood-clot + PRP group.

Whole blood clot and PRP are comparable on the grounds of percentage change in RRA and there is no statistically significant difference between the two in a follow-up period of up to one year.