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Related Experiment Video

Updated: Nov 3, 2025

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

Vanishing bone disease: An enigma.

Fatema Yusuf Saify¹, Suchitra Gosavi², Shilpa Jain³

¹Department of Oral Pathology, Government Dental College, Raipur, Chattisgarh, India.

Journal of Oral and Maxillofacial Pathology : JOMFP

|June 4, 2021

Summary

This summary is machine-generated.

Vanishing bone disease, also known as Gorham's disease, is a rare condition causing bone loss. This report details a unique case of massive osteolysis affecting the lower jaw.

Keywords:

Gorham's disease mandible massive osteolysis vanishing bone disease

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Area of Science:

Rare diseases
Skeletal pathology
Medical case reports

Background:

Vanishing bone disease (Gorham's disease) is a rare condition characterized by progressive bone loss.
Its etiology and pathogenesis remain largely unknown, affecting individuals of any age or sex.
The condition is also referred to as phantom bone disease, massive osteolysis, or disappearing bone disease.

Observation:

This report presents a unique case of massive osteolysis affecting the mandibular basal and alveolar bone.
The condition manifested as significant bone loss in the lower jaw.
Diagnosis was established through a combination of clinical, radiological, and histological assessments.

Findings:

The case highlights the potential for massive osteolysis to impact the jawbone.
The diagnosis was confirmed by integrating clinical presentation, imaging studies, and tissue analysis.
This unique presentation adds to the limited understanding of vanishing bone disease.

Implications:

This case underscores the importance of considering rare skeletal diseases like Gorham's disease in differential diagnoses.
Further research into the pathogenesis of massive osteolysis is needed for effective treatment strategies.
Reporting unique cases contributes valuable data for understanding and managing this rare condition.