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Articles linked to this work by shared authors, journal, and citation graph.

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RETINAL MICROCIRCULATION INVESTIGATION IN TYPE I AND II DIABETIC PATIENTS WITHOUT RETINOPATHY USING AN ADAPTIVE OPTICS RETINAL CAMERA.

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Effect of A Multinutrient Complex on Retinal Microcirculation in Diabetic Patients Investigated Using an Adaptive

F Baltã1,2,3, I E Cristescu3, A E Mirescu2

  • 1"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.

Acta Endocrinologica (Bucharest, Romania : 2005)
|June 4, 2021
PubMed
Summary

This study found that the multinutrient supplement Resvega improved retinal arteriole health in diabetic patients after three months. Resvega positively impacted the wall-to-lumen ratio, wall thickness, and cross-sectional area of retinal arterioles.

Keywords:
adaptive optics ophthalmoscopydiabetic retinopathyoptical coherence tomography angiographyresveratrol

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Area of Science:

  • Ophthalmology
  • Diabetology
  • Nutritional Science

Background:

  • Diabetic patients often experience microvascular complications affecting the retina.
  • Alimentary supplements show potential for improving retinal microvasculature in diabetes.

Purpose of the Study:

  • To evaluate the effect of a multinutrient complex (Resvega) on retinal microcirculation in diabetic patients.
  • To assess changes in retinal arterioles and capillary plexuses using advanced imaging techniques before and after a 3-month treatment period.

Main Methods:

  • Observational study involving 15 diabetic patients.
  • Adaptive optics ophthalmoscopy to measure temporal retinal arteriole parameters.
  • Optical coherence tomography angiography (OCTA) to assess foveal avascular zone and vessel densities.

Main Results:

  • A statistically significant decrease in the wall-to-lumen ratio of retinal arterioles was observed (p=0.0001).
  • Significant reductions in arteriole wall thickness (p=0.008) and wall cross-sectional area (p=0.001) were also noted.
  • No significant changes were detected in OCTA parameters of the capillary plexuses.

Conclusions:

  • The multinutrient supplement Resvega demonstrated a beneficial effect on retinal arterioles in diabetic patients.
  • Resvega may help mitigate microvascular changes in the retina associated with diabetes.